The Web3 ecosystem continues to expand at a rapid pace, with developers and enterprises seeking seamless access to multiple blockchain networks through unified, scalable, and secure infrastructure. Whether you're building decentralized applications (dApps), digital asset platforms, or blockchain-based marketplaces, integration with a comprehensive Web3 API solution is essential for success.
This guide provides an in-depth overview of the supported networks across key Web3 service categories: Wallet API, DEX API, Marketplace API, and DeFi API. These services are part of a robust Web3 infrastructure platform designed to simplify blockchain development and accelerate time-to-market.
Comprehensive Multi-Chain Support
Modern Web3 applications must operate across multiple blockchains to reach diverse user bases, reduce transaction costs, and leverage unique network features such as scalability, speed, or specialized use cases like gaming or NFTs. The supported networks span leading Layer 1 and Layer 2 blockchains, including Ethereum, BNB Smart Chain, Polygon, Arbitrum, zkSync, and many emerging chains.
Each chain is evaluated based on its support level for core APIs:
- Wallet API: Enables wallet creation, balance tracking, transaction signing, and on-chain interaction.
- DEX API: Facilitates decentralized exchange functions such as token swaps and cross-chain bridging.
- Marketplace API: Powers NFT minting, listing, bidding, and trading functionalities.
- DeFi API: Supports lending, borrowing, staking, yield farming, and other decentralized finance operations.
👉 Discover how multi-chain API support can streamline your dApp development
Fully Supported Networks
The following networks offer complete or near-complete support across all four major API types:
- Ethereum Mainnet – The foundational blockchain for DeFi and NFTs, offering full support across Wallet, DEX, Marketplace, and DeFi APIs.
- OP Mainnet (Optimism) – A leading optimistic rollup with robust support for swap and cross-chain functionality.
- BNB Smart Chain Mainnet – High-performance chain ideal for low-cost transactions and DeFi applications.
- Polygon Mainnet – Popular scaling solution with strong ecosystem adoption and full API integration.
- Arbitrum One – One of the most widely used Layer 2 solutions, supporting advanced DeFi and cross-chain use cases.
- Avalanche C-Chain – Known for fast finality and high throughput, fully integrated into the API suite.
- zkSync Era Mainnet – ZK-rollup enabling scalable and private transactions with full wallet and DEX support.
- Base – Coinbase’s Ethereum Layer 2, gaining traction with full wallet and DEX capabilities.
- Linea – ConsenSys-built ZK-EVM with growing developer support and full API access.
- Manta Pacific Mainnet – Privacy-focused zkLighthouse-based chain with full-service availability.
These chains represent the backbone of today’s Web3 development landscape, offering developers the tools needed to build scalable, interoperable applications.
Partially Supported Networks
Some chains provide support for specific APIs depending on ecosystem maturity and integration priorities:
- OKT Chain & X Layer: Both support Wallet, Marketplace, and DeFi APIs. DEX support includes token swaps but may lack advanced cross-chain routing.
- Fantom Opera: Offers strong Wallet and DeFi integration, with DEX swap functionality available.
- Mantle: Supports Wallet and DeFi APIs along with DEX swaps and cross-chain capabilities.
- Scroll & Blast: Emerging Ethereum Layer 2s with Wallet and DEX API support; Marketplace integration is active on Scroll.
- opBNB Mainnet: Optimized for high-throughput dApps; supports Wallet, Marketplace, and DeFi APIs.
- Gnosis & Core Blockchain: Focused on DeFi and secure transactions with Wallet and DeFi API availability.
Developers targeting niche or high-performance chains will find that core functionalities remain accessible even if not all services are enabled.
Emerging and Specialized Chains
A growing number of innovative networks are being integrated to support next-generation use cases:
- Taiko, Bitlayer, Bob, Mode, and Kava EVM – New Layer 1/Layer 2 projects with Wallet API support, laying the foundation for future expansions.
- Immutable zkEVM – Tailored for gaming and NFTs; currently supports wallet operations.
- Cronos, Wemix, Rangers, and Ronin – Gaming-centric blockchains where wallet infrastructure is prioritized.
- ZetaChain & Sonic – Unique interoperability-focused chains offering DEX swap and cross-chain routing without wallet creation support yet.
These networks reflect the evolving nature of blockchain technology — from finance to gaming, identity, and cross-chain communication.
👉 Explore how emerging chains can give your project a first-mover advantage
Developer Benefits of Broad Chain Support
Access to over 40+ blockchains through a single API interface delivers significant advantages:
- Unified Integration: No need to manage multiple SDKs or node providers.
- Reduced Development Time: Pre-built endpoints for common operations accelerate prototyping and deployment.
- Cross-Chain Interoperability: Built-in DEX aggregation enables seamless asset transfers across ecosystems.
- Scalability & Flexibility: Deploy across mainnets, testnets (e.g., Sepolia), and Layer 2s using consistent tooling.
For startups and enterprises alike, this level of support lowers technical barriers and opens doors to global Web3 innovation.
Frequently Asked Questions (FAQ)
What does "Supported" mean for each API type?
"Supported" indicates that stable, production-ready endpoints are available for that service on the specified chain. This includes documented methods, reliable uptime, and active maintenance.
Are testnets included in the supported list?
Yes. For example, Sepolia is listed as supporting Wallet API functions, allowing developers to test integrations before going live on Ethereum Mainnet.
Why isn’t DeFi API available on some major chains?
API availability depends on ecosystem demand, smart contract compatibility, and protocol partnerships. Support is continuously expanding based on developer feedback.
Can I perform cross-chain swaps between all supported networks?
Cross-chain swaps are available via the DEX API on chains where it's marked as "Supported: Swap & Cross-chain." Availability depends on liquidity routes and bridge integrations.
How often is the list of supported networks updated?
The network list is updated regularly as new blockchains gain traction or reach technical readiness. Developers are encouraged to check release notes for additions.
Is there a way to request support for a new chain?
Yes. Development teams can submit feature requests through official developer portals to prioritize integration of new networks.
Final Thoughts
The breadth of supported networks underscores a commitment to open, accessible Web3 infrastructure. From Ethereum’s established ecosystem to cutting-edge ZK-rollups and gaming chains, developers have unprecedented access to tools that power innovation.
By leveraging a unified API framework across dozens of blockchains, teams can focus less on infrastructure complexity and more on creating exceptional user experiences.
👉 Start building across multiple chains with powerful Web3 APIs today